Biology

Janette Gomos Klein Doctoral Lecturer EMail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it Office: Room 818 HN Phone: (212) 396-6252

Education:

• PhD (Biological Sciences), CUNY 

Research Interest

• Science education,

Selected Publications

• S. Knirr¹, J. Gomos-Klein¹, B. Andino, F. Harrow, K. Erhard, D. Kovalovsky, D. Sant’Angelo, B. Ortiz. Ectopic TCRα Locus Control Region Activity in B cells is Suppressed by Direct Linkage to Two Flanking Genes at Once. ¹contributed equally PLoS One. 5(11):e15527.
• J. Gomos-Klein, F. Harrow, J. Alarcón, B.D. Ortiz. CTCF- independent elements confer insulation capacity to the TCRa locus control region. J Immunol, 2007 Jul 15; 179(2):1088-95.
• M. Murphy¹, J. Gomos-Klein¹, M. Stankic, E. Falck-Pedersen. The p5 promoter: A DNA switch that determines integrative vs. productive pathways in the AAV2 lifecycle. J Virol. 2007 Apr; 81(8):3721-30. ¹contributed equally.
• H. Hamilton, J. Gomos, K.I. Berns, E. Falck-Pedersen. Adeno-associated virus site-specific integration and AAVS1 disruption. J Virol. 2004 Aug; 78(15):7874-82
• N.J. Philpott, J. Gomos, E. Falck-Pedersen. Transgene expression after rep-mediated site-specific integration into chromosome 19. Hum Gene Ther. 2004 Jan; 15(1):47-61.
• S.P. Kessler, P. deS Senanayake, TS. Scheidemantel, J.B. Gomos, T.M. Rowe, G.C. Sen. Maintenance of normal blood pressure and renal functions are independent effects of angiotensin- converting enzyme. J Biol Chem. 2003 Jun 6; 278(23): 21105-12.
• N.J. Philpott, J. Gomos, K.I. Berns, E. Falck-Pedersen. A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12381-5.
• N.J. Philpott, C. Giraud-Wali, C. Dupuis, J. Gomos, H. Hamilton, K.I. Berns, E. Falck-Pedersen. Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis. J Virol. 2002 Jun;76(11):5411-21.
• S.P. Kessler, J.B. Gomos, T.S. Scheidemantel, T.M. Rowe, H.L. Smith, and G.C. Sen. The Germinal Isozyme of Angiotensin-converting Enzyme Can Substitute for the Somatic Isozyme in Maintaining Normal Renal Structure and Functions. J Biol Chem. 2002 Feb 8; 277(6): 4271-4276.
• J.B. Gomos, T.M. Rowe, S.N. Sarkar, S.P. Kessler, and G.C. Sen. The Pro-Apoptotic 9-2 Isozyme of 2-5 (A) Sythnetase Cannot Substitute for the Sprem Function of the Pro- Apoptotic Protein, Bax. J Interferon and Cytokine Res. 2002 Feb; 22(2):199-206
• S.P. Kessler, T.M. Rowe, J.B. Gomos, P.M. Kessler, and G.C. Sen.  Physiological Non-equivalence of the Two Isoforms of Angiotensin-converting Enzyme.  J Biol Chem. 2000 Aug 25; 275 (34): 26259-26264.